Levodopa, L-DOPA
Description:
L-DOPA, also known as levodopa and l-3,4-dihydroxyphenylalanine, is an amino acid that is made an  d used as part of the normal biology of humans, as well as some animals and plants. Humans, as well as a portion of the other animals that utilize l-DOPA in their biology, make it via biosynthesis from the amino acid l-tyrosine. l-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. Furthermore, l-DOPA itself mediates neurotrophic factor release by the brain and CNS.l-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Pharmacopa, Atamet, and Stalevo. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.
Product Name
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Levodopa
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CAS
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59-92-7
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MF
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C9H11NO4
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MW
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197.19
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EINECS
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200-445-2
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Melting point
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276-278 °C
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Boiling point
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334.28°C
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Density
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1.3075
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pka
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2.32(at 25℃)
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l-DOPA has a counterpart with opposite chirality, d-DOPA. As is true for many molecules, the human body produces only one of these isomers (the l-DOPA form). The enantiomeric purity of l-DOPA may be analyzed by determination of the optical rotation or by chiral thin-layer chromatography (chiral TLC).
Function:
1 ) L-DOPA is anti-paralysis agitans. Through the blood-brain barrier into the brain tissue, but by the decarboxylation of dopa decarboxylase into dopamine, play a role.
2) L-DOPA can be used for essential tremor and paralysis paralysis agitans syndrome of non-drug immunogenicity, and in better light, severe, or the elderly poor.
3) L-DOPA can promote muscle growth,loss weight.
4) L-DOPA can increase bone density and reversal of osteoporosis.
5) L-DOPA can be dietary supplements.
6) L-DOPA can treat parkinsonism and Pakinsonism syndrome, hepatic coma,hub functions to improve the patient awake, symptom improvement.
7) L-DOPA can promote sleep,improve immune system.
8) L-DOPA can weight loss.
9)L-DOPA can increase bone density and reversal of osteoporosis,increase muscle strength,enhance libido and sexual performance
Application:
1)Levodopa can be used as dietary supplements.
2)Levodopa is used as a component in marine adhesives used by pelagic life.
3)Levodopa can promote muscle growth,loss weight,and increased bone density and reversal of osteoporosis.
4)Levodopa increase bone density and reversal of osteoporosis,increase muscle strength,enhance libido and sexual performance.
5) In clinical use, Levodopa is administered in the management of Parkinson's disease and dopa-responsive dystonia.
6) For essential tremor and paralysis paralysis agitans syndrome of non-drug immunogenicity, and in better light, severe, or the elderly poor.
7)Treat parkinsonism and Pakinsonism syndrome, hepatic coma,hub functions to improve the patient awake, symptom improvement.
8)Levodopa is anti-paralysis agitans. Through the blood-brain barrier into the brain tissue, but by the decarboxylation of l-dopa decarboxylase into dopamine, play a role.
9)Levodopa is used for essential tremor and paralysis paralysis agitans syndrome of non-drug immunogenicity, and in better light, severe, or the elderly poor. |